Globálny slovník portálu IMED

Pojem: 
Karcinom
Definícia: 

Karcinom (z řeckého karkinôma) je nádorové onemocnění, vycházející z epitelu, tedy např. z vrstev kůže či sliznic, jde tedy o nádory z tkání ektodermálního či entodermálního původu. Většina karcinomů pochází z krycího epitelu, nebo žlázového epitelu. Karcinomy tvoří cca 80% maligních nádorů.

Kľúčové slovo: 
Nádorové onemocnění
Pojem: 
Kapsida
Definícia: 

Kapsida, též kapsid, je obal virionové částice. Skládá se z proteinových podjednotek – kapsomer – a obklopuje nukleovou kyselinu (DNA nebo RNA) viru. Kapsida má ochrannou funkci a zaniká, jakmile virus dosáhne hostitelské buňky a počne se replikovat. Proteiny kapsidy představují řadu antigenů, proti kterým organismus vytváří protilátky.

Kategória:

Kľúčové slovo: 
Obal virionové částice
Pojem: 
Dysurie
Definícia: 

Dysurie je pálivá a řezavá bolest vycházející z močové trubice nebo jejího okolí při močení. Mezi její příčiny se řadí: lokální podráždění ústí močové trubice (intertrigo, balanitida, vulvovaginitida, užití nevhodných mýdel nebo přísad do koupelí), evakuace příliš koncentrované moči (dehydratace), zánět dolních močových cest (cystitida, uretritida), užití léků dráždících sliznici močového měchýře (sulfonamidy, cyklofosfamid, amitriptylin).

Kľúčové slovo: 
Pálivá a řezavá bolest při močení
Pojem: 
genetický polymorfismus
Definícia: 

Existence dvou nebo více alel (variant genů) v jednom lokusu, převyšující svým výskytem 1% výskyt v populaci. Příčinou přitom nejsou opakovaně probíhající mutace.

Kľúčové slovo: 
varianta genu
Pojem: 
Asociační studie
Definícia: 

<span style="\&quot;font-size:" 12pt;="" font-family:="" &quot;arial&quot;,&quot;sans-serif&quot;;\"="">studie, která testuje vztah mezi konkrétní alelou, genotypem nebo haplotypem (souborem úzce vázaných genotypů) a onemocněním.

Kategória:

Kľúčové slovo: 
alela
Pojem: 
Genotoxická látka
Definícia: 

 

<p style="\&quot;text-align:" justify;\"=""> Látka, ktorá spôsobuje zmenu genetického materiálu v jeho štruktúre alebo sekvencii báz na úrovni nukleových kyselín génov alebo chromozómov.

Kľúčové slovo: 
Genotoxická látka
Pojem: 
Genetická toxikológia
Definícia: 

 

<p style="\&quot;text-align:" justify;\"=""> Interdisciplinárna veda, ktorej predmetom je identifikácia mutagénneho a karcinogénneho účinku chemických, fyzikálnych a biologických agensov a ich dopad na zdravie a genetický materiál človeka.

Kľúčové slovo: 
Genetická toxikológia
Pojem: 
Genetické riziko
Definícia: 

 

<p style="\&quot;text-align:" justify;\"=""> Schopnosť environmentálneho faktora vyvolávať v pohlavných bunkách človeka mutácie, ktoré determináciou dedičných ochorení negatívne ovplyvňujú kvalitu ľudského genofondu, zvyšujú reprodukčné straty a uplatňujú sa pri niektorých druhoch vrodených defektov a vývojových chýb.

Kľúčové slovo: 
Genetické riziko
Pojem: 
Dedičné poruchy metabolizmu lyzozómov
Definícia: 

<p>
Do skupiny lyzoz&oacute;mov&yacute;ch ochoren&iacute; patr&iacute; viac ako 40 nozologick&yacute;ch jednotiek, ktor&eacute; m&ocirc;žu byť sp&ocirc;soben&eacute;: 1. zn&iacute;ženou aktivitou enz&yacute;mov potrebn&yacute;ch na intracelul&aacute;rnu degrad&aacute;ciu vysokomolekulov&yacute;ch l&aacute;tok, 2. defektom lyzoz&oacute;mov&eacute;ho transportu l&aacute;tok, 3. ch&yacute;ban&iacute;m receptora pre man&oacute;zo-6-fosf&aacute;t, ktor&yacute; je potrebn&yacute; k presunu en&yacute;mov z cytoplazmy do lyzoz&oacute;mov. V d&ocirc;sledku defektu metabolizmu sa nekompletne degradovan&eacute; metabolity hromadia v lyzoz&oacute;moch.</p>
<p>
&nbsp;</p>

Pojem: 
juvenilný
Definícia: 

mladistvý, začínajúci v mladosti

 

Kľúčové slovo: 
juvenilný
Pojem: 
idiopatický
Definícia: 

neznámeho pôvodu

 

Kľúčové slovo: 
idiopatický
Pojem: 
Incidencia
Definícia: 

<p><span style=\"font-size: 12.0pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;; mso-fareast-font-family: &quot;Times New Roman&quot;; mso-ansi-language: SK; mso-fareast-language: SK; mso-bidi-language: AR-SA;\">Počet nov&yacute;ch pr&iacute;padov ochorenia za určit&eacute; časov&eacute; obdobie</span></p>

Kľúčové slovo: 
Incidencia
Pojem: 
Anafylaxia
Definícia: 

<p><span style=\"font-size: 12.0pt; font-family: &quot;Times New Roman&quot;,&quot;serif&quot;; mso-fareast-font-family: &quot;Times New Roman&quot;; mso-ansi-language: SK; mso-fareast-language: SK; mso-bidi-language: AR-SA;\">Ak&uacute;tna alergick&aacute; reakcia, ktor&aacute; vznik&aacute; na podklade imunopatologickej reakcie I. typu, sprostredkovanej protil&aacute;tkami IgE. Najťaž&scaron;ou, život ohrozuj&uacute;cou formou anafylaktickej reakcie je anafylaktick&yacute; &scaron;ok.</span></p>

Kľúčové slovo: 
Anafylaxia
Pojem: 
DIC
Definícia: 

<p>&nbsp;</p>
<p class=\"MsoNormal\" style=\"text-align: justify; line-height: 150%;\">Koagulačn&aacute; dysbalancia medzi prokoagulačnou aktivitou tromb&iacute;nu a&nbsp;fibrinolytickou aktivitou plazm&iacute;nu, rezultuj&uacute;ca v&nbsp;intravaskul&aacute;rnu tvorbu fibr&iacute;nu s&nbsp;trombotick&yacute;mi okl&uacute;ziami v&nbsp;mikrocirkul&aacute;cii, s&nbsp;n&aacute;slednou org&aacute;novou ischemiz&aacute;ciou, konzumpciou koagulačn&yacute;ch faktorov a&nbsp;krv&aacute;can&iacute;m.</p>
<p>&nbsp;</p>

Kľúčové slovo: 
DIC
Pojem: 
demyelinizační onemocnění CNS
Definícia: 

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Name=\"Medium Grid 2 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"19\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Subtle Emphasis\" /> <w:LsdException Locked=\"false\" Priority=\"21\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Intense Emphasis\" /> <w:LsdException Locked=\"false\" Priority=\"31\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Subtle Reference\" /> <w:LsdException Locked=\"false\" Priority=\"32\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Intense Reference\" /> <w:LsdException Locked=\"false\" Priority=\"33\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Book Title\" /> <w:LsdException Locked=\"false\" Priority=\"37\" Name=\"Bibliography\" /> <w:LsdException Locked=\"false\" Priority=\"39\" QFormat=\"true\" Name=\"TOC Heading\" /> </w:LatentStyles> </xml><![endif]--><!--[if gte mso 10]> <mce:style><! /* Style Definitions */ table.MsoNormalTable {mso-style-name:\"Norm&aacute;ln&iacute; tabulka\"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:\"\"; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:\"Calibri\",\"sans-serif\"; mso-bidi-font-family:Arial;} --> <!--[endif] --><span style=\"font-size: 12pt; line-height: 150%; font-family: &quot;Calibri&quot;,&quot;sans-serif&quot;; color: black;\">charakterizov&aacute;ny rozpadem myelinu v&nbsp;centr&aacute;ln&iacute;m nervov&eacute;m syst&eacute;mu, pravidelně v&scaron;ak i současnou ztr&aacute;tou axonů</span></p>

Kľúčové slovo: 
demyelinizační
Pojem: 
roztroušená skleróza
Definícia: 

<p><!--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:DoNotShowComments /> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF /> <w:LidThemeOther>CS</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>AR-SA</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> <w:SplitPgBreakAndParaMark /> <w:DontVertAlignCellWithSp /> <w:DontBreakConstrainedForcedTables /> <w:DontVertAlignInTxbx /> <w:Word11KerningPairs /> <w:CachedColBalance /> </w:Compatibility> <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel> <m:mathPr> <m:mathFont m:val=\"Cambria Math\" /> <m:brkBin m:val=\"before\" /> <m:brkBinSub m:val=\"&#45;-\" /> <m:smallFrac m:val=\"off\" /> <m:dispDef /> <m:lMargin m:val=\"0\" /> <m:rMargin m:val=\"0\" /> <m:defJc m:val=\"centerGroup\" /> <m:wrapIndent m:val=\"1440\" /> <m:intLim m:val=\"subSup\" /> <m:naryLim m:val=\"undOvr\" /> </m:mathPr></w:WordDocument> </xml><![endif]--><!--[if gte mso 9]><xml> <w:LatentStyles DefLockedState=\"false\" DefUnhideWhenUsed=\"true\" DefSemiHidden=\"true\" DefQFormat=\"false\" DefPriority=\"99\" LatentStyleCount=\"267\"> <w:LsdException Locked=\"false\" Priority=\"0\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Normal\" /> <w:LsdException Locked=\"false\" Priority=\"9\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"heading 1\" /> <w:LsdException Locked=\"false\" Priority=\"0\" QFormat=\"true\" Name=\"heading 2\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 3\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 4\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 5\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 6\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 7\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 8\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 9\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 1\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 2\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 3\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 4\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 5\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 6\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 7\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 8\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 9\" /> <w:LsdException Locked=\"false\" Priority=\"35\" QFormat=\"true\" Name=\"caption\" /> <w:LsdException Locked=\"false\" Priority=\"10\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Title\" /> <w:LsdException Locked=\"false\" Priority=\"1\" Name=\"Default Paragraph Font\" /> <w:LsdException Locked=\"false\" Priority=\"0\" Name=\"Body Text\" /> <w:LsdException Locked=\"false\" Priority=\"11\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Subtitle\" /> <w:LsdException Locked=\"false\" Priority=\"0\" Name=\"Block Text\" /> <w:LsdException Locked=\"false\" Priority=\"0\" Name=\"Hyperlink\" /> <w:LsdException Locked=\"false\" Priority=\"0\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Strong\" /> <w:LsdException Locked=\"false\" Priority=\"20\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Emphasis\" /> <w:LsdException Locked=\"false\" Priority=\"0\" Name=\"Plain Text\" /> <w:LsdException Locked=\"false\" Priority=\"59\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Table Grid\" /> <w:LsdException Locked=\"false\" UnhideWhenUsed=\"false\" Name=\"Placeholder Text\" /> <w:LsdException Locked=\"false\" Priority=\"1\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"No Spacing\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1 Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2 Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1 Accent 1\" /> <w:LsdException Locked=\"false\" UnhideWhenUsed=\"false\" Name=\"Revision\" /> <w:LsdException Locked=\"false\" Priority=\"34\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"List Paragraph\" /> <w:LsdException Locked=\"false\" Priority=\"29\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Quote\" /> <w:LsdException Locked=\"false\" Priority=\"30\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Intense Quote\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2 Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1 Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2 Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3 Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"19\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Subtle Emphasis\" /> <w:LsdException Locked=\"false\" Priority=\"21\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Intense Emphasis\" /> <w:LsdException Locked=\"false\" Priority=\"31\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Subtle Reference\" /> <w:LsdException Locked=\"false\" Priority=\"32\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Intense Reference\" /> <w:LsdException Locked=\"false\" Priority=\"33\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Book Title\" /> <w:LsdException Locked=\"false\" Priority=\"37\" Name=\"Bibliography\" /> <w:LsdException Locked=\"false\" Priority=\"39\" QFormat=\"true\" Name=\"TOC Heading\" /> </w:LatentStyles> </xml><![endif]--><!--[if gte mso 10]>
<style>
/* Style Definitions */
table.MsoNormalTable
{mso-style-name:\"Normální tabulka\";
mso-tstyle-rowband-size:0;
mso-tstyle-colband-size:0;
mso-style-noshow:yes;
mso-style-priority:99;
mso-style-qformat:yes;
mso-style-parent:\"\";
mso-padding-alt:0cm 5.4pt 0cm 5.4pt;
mso-para-margin:0cm;
mso-para-margin-bottom:.0001pt;
mso-pagination:widow-orphan;
font-size:10.0pt;
font-family:\"Calibri\",\"sans-serif\";
mso-bidi-font-family:Arial;}
</style>
<![endif]--><span style=\"font-size: 12pt; line-height: 150%; font-family: &quot;Calibri&quot;,&quot;sans-serif&quot;; color: black;\">chronick&eacute; z&aacute;nětliv&eacute; onemocněn&iacute; CNS autoimunitn&iacute; povahy s&nbsp;&uacute;čast&iacute; neurodegenerace vedouc&iacute; k&nbsp;destrukci myelinu (demyelinizaci) a dif&uacute;zn&iacute; ztr&aacute;tě axonů (axon&aacute;ln&iacute; l&eacute;zi).</span></p>

Kľúčové slovo: 
roztroušená skleróza
Pojem: 
T-lymfocyty
Definícia: 

<p><!--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:DoNotShowComments /> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF /> <w:LidThemeOther>CS</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>AR-SA</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> <w:SplitPgBreakAndParaMark /> <w:DontVertAlignCellWithSp /> <w:DontBreakConstrainedForcedTables /> <w:DontVertAlignInTxbx /> <w:Word11KerningPairs /> <w:CachedColBalance /> </w:Compatibility> <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel> <m:mathPr> <m:mathFont m:val=\"Cambria Math\" /> <m:brkBin m:val=\"before\" /> <m:brkBinSub m:val=\"&#45;-\" /> <m:smallFrac m:val=\"off\" /> <m:dispDef /> <m:lMargin m:val=\"0\" /> <m:rMargin m:val=\"0\" /> <m:defJc m:val=\"centerGroup\" /> <m:wrapIndent m:val=\"1440\" /> <m:intLim m:val=\"subSup\" /> <m:naryLim m:val=\"undOvr\" /> </m:mathPr></w:WordDocument> </xml><![endif]--><!--[if gte mso 9]><xml> <w:LatentStyles DefLockedState=\"false\" DefUnhideWhenUsed=\"true\" DefSemiHidden=\"true\" DefQFormat=\"false\" DefPriority=\"99\" LatentStyleCount=\"267\"> <w:LsdException Locked=\"false\" Priority=\"0\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Normal\" /> <w:LsdException Locked=\"false\" Priority=\"9\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"heading 1\" /> <w:LsdException Locked=\"false\" Priority=\"0\" QFormat=\"true\" Name=\"heading 2\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 3\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 4\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 5\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 6\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 7\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 8\" /> <w:LsdException Locked=\"false\" Priority=\"9\" QFormat=\"true\" Name=\"heading 9\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 1\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 2\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 3\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 4\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 5\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 6\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 7\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 8\" /> <w:LsdException Locked=\"false\" Priority=\"39\" Name=\"toc 9\" /> <w:LsdException Locked=\"false\" Priority=\"35\" QFormat=\"true\" Name=\"caption\" /> <w:LsdException Locked=\"false\" Priority=\"10\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Title\" /> <w:LsdException Locked=\"false\" Priority=\"1\" Name=\"Default Paragraph Font\" /> <w:LsdException Locked=\"false\" Priority=\"0\" Name=\"Body Text\" /> <w:LsdException Locked=\"false\" Priority=\"11\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Subtitle\" /> <w:LsdException Locked=\"false\" Priority=\"0\" Name=\"Block Text\" /> <w:LsdException Locked=\"false\" Priority=\"0\" Name=\"Hyperlink\" /> <w:LsdException Locked=\"false\" Priority=\"0\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Strong\" /> <w:LsdException Locked=\"false\" Priority=\"20\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Emphasis\" /> <w:LsdException Locked=\"false\" Priority=\"0\" Name=\"Plain Text\" /> <w:LsdException Locked=\"false\" Priority=\"59\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Table Grid\" /> <w:LsdException Locked=\"false\" UnhideWhenUsed=\"false\" Name=\"Placeholder Text\" /> <w:LsdException Locked=\"false\" Priority=\"1\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"No Spacing\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1 Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2 Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1 Accent 1\" /> <w:LsdException Locked=\"false\" UnhideWhenUsed=\"false\" Name=\"Revision\" /> <w:LsdException Locked=\"false\" Priority=\"34\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"List Paragraph\" /> <w:LsdException Locked=\"false\" Priority=\"29\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Quote\" /> <w:LsdException Locked=\"false\" Priority=\"30\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Intense Quote\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2 Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1 Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2 Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3 Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid Accent 1\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3 Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid Accent 2\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3 Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid Accent 3\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3 Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid Accent 4\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3 Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid Accent 5\" /> <w:LsdException Locked=\"false\" Priority=\"60\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Shading Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"61\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light List Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"62\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Light Grid Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"63\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 1 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"64\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Shading 2 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"65\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 1 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"66\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium List 2 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"67\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 1 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"68\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 2 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"69\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Medium Grid 3 Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"70\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Dark List Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"71\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Shading Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"72\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful List Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"73\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" Name=\"Colorful Grid Accent 6\" /> <w:LsdException Locked=\"false\" Priority=\"19\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Subtle Emphasis\" /> <w:LsdException Locked=\"false\" Priority=\"21\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Intense Emphasis\" /> <w:LsdException Locked=\"false\" Priority=\"31\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Subtle Reference\" /> <w:LsdException Locked=\"false\" Priority=\"32\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Intense Reference\" /> <w:LsdException Locked=\"false\" Priority=\"33\" SemiHidden=\"false\" UnhideWhenUsed=\"false\" QFormat=\"true\" Name=\"Book Title\" /> <w:LsdException Locked=\"false\" Priority=\"37\" Name=\"Bibliography\" /> <w:LsdException Locked=\"false\" Priority=\"39\" QFormat=\"true\" Name=\"TOC Heading\" /> </w:LatentStyles> </xml><![endif]--><!--[if gte mso 10]>
<style>
/* Style Definitions */
table.MsoNormalTable
{mso-style-name:\"Normální tabulka\";
mso-tstyle-rowband-size:0;
mso-tstyle-colband-size:0;
mso-style-noshow:yes;
mso-style-priority:99;
mso-style-qformat:yes;
mso-style-parent:\"\";
mso-padding-alt:0cm 5.4pt 0cm 5.4pt;
mso-para-margin:0cm;
mso-para-margin-bottom:.0001pt;
mso-pagination:widow-orphan;
font-size:10.0pt;
font-family:\"Calibri\",\"sans-serif\";
mso-bidi-font-family:Arial;}
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<![endif]--></p>
<p class=\"Obsahtabuky\" style=\"margin-left: 36pt; text-align: justify; text-indent: -18pt;\"><span style=\"font-size: 14pt; font-family: &quot;Calibri&quot;,&quot;sans-serif&quot;; color: black;\" lang=\"SK\"><span></span></span><span style=\"font-family: &quot;Calibri&quot;,&quot;sans-serif&quot;; color: black;\" lang=\"SK\">za in<span>ici&aacute;tory onemocněn&iacute; jsou považov&aacute;ny autoagresivn&iacute; T-lymfocyty rozpozn&aacute;vaj&iacute;c&iacute; myelinov&eacute; antigeny, kter&eacute; jsou<span>&nbsp; </span>u pacientů s&nbsp;RS schopny aktivace a proliferace v&nbsp;takov&eacute;m množstv&iacute;, kter&eacute; je kritick&eacute; pro zah&aacute;jen&iacute; autoimunitn&iacute; reakce. </span></span></p>

Kľúčové slovo: 
T-lymfocyty
Pojem: 
hemato-likvorová bariéra
Definícia: 

<p>bari&eacute;ra mezi krv&iacute; a likvorov&yacute;mi cestami</p>

Kľúčové slovo: 
hemato-likvorová bariéra
Pojem: 
retrobulbární optická neuritida
Definícia: 

<p>z&aacute;nět zrakov&eacute;ho nervu, kter&yacute; může způsobit &uacute;plnou nebo č&aacute;stečnou ztr&aacute;tu zraku<a title=\"Zrak\" href=\"http://cs.wikipedia.org/wiki/Zrak\"></a></p>

Kľúčové slovo: 
retrobulbární optická neuritida

Stránky